Irrespective of the type of wound and the extent of tissue loss, the wound-healing process takes place in three dynamic stages: the cleansing phase, the granulation phase (tissue formation) and the epithelisation phase (epidermisation). In chronic wounds – ones that show little or no sign of healing, despite appropriate therapy, within an acceptable time frame - this healthy healing process is disturbed and tissue regeneration is delayed.
Stage 1: Cleansing Phase
Once the initial bleeding stops, white blood corpuscles can migrate more easily into the wound as blood vessels dilate and the vascular walls become more permeable. It is their task to defend against infection and to cleanse the wound.
At this stage the priority is to remove avital (non-vital) and necrotic tissue, to promote wound cleansing, and remove bacteria and toxins that could contribute to delayed healing.
Stage 2: Granulation Phase
The tissue from deep defects cannot regenerate so, during this period, a wound defect is filled with new tissue. The Granulation Phase describes the regeneration of tissue, when the wound is filled from the inside.
The priority here is to protect the new tissue and prevent wound desiccation. If the wound dries out, cells die. Permanent levels of hydration maintain the healing process.


