Enveloped viruses Non-enveloped viruses After disinfection After disinfection Lipid envelope is no longer functional Capsid is no longer functional Fragile outer envelope, easy for the disinfectant to destroy Robust capsule containing genetic information. More difficult for disinfectants to destroy Lipid membrane Capsid Efficacies of disinfectants: Viruses Level 1 easy to inactivate virucidal activity against enveloped viruses All enveloped viruses spectrum of efficacy Examples of enveloped viruses Examples of non-enveloped viruses SARS CoV-2 Influenza viruses Hepatitis B viruses Level 2 a little more difficult to inactivate limited spectrum virucidal activity All enveloped viruses + these 3 non-enveloped viruses spectrum of efficacy Adenoviruses Noroviruses Rotaviruses Level 3 most difficult to inactivate virucidal All enveloped viruses + all non-enveloped viruses spectrum of efficacy Polioviruses human Papillomaviruses Polyomaviruses HSC EN 02.22 3
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