HydroClean® Plus

Real Life Evidence of a Hydro‑Responsive Wound Dressing for wound
bed preparation


Assess the effectiveness of Hydro-Responsive Wound Dressing (HRWD™) in debridement and wound bed preparation.

Design:Non-comparative multi-center evaluation
Number of patients:100
Types of Wounds:54.9% Chronic Wounds,

31.5% Acute Wounds,

13.5% Other Types of Wounds
Location:Glasgow and Clyde Regions, UK

HydroClean® plus - The Glasgow Experience

Promote autolytic debridement:

More than 90% of the clinicians reported that the removal of devitalized tissue had been achieved.[1]

Devitalized tissue (necrosis and slough) reduced about 69% accompanied by an increase in wound bed granulation tissue of over 280%*[1]

Reduce pain: 

More than 3 in 4 (76.1%) patients experienced no pain during wear time.[1]

Nearly 50% of patients who did experience pain reported a significant improvement.[1]


Savings per patient of using HRWD vs. honey (A), larval (B) and mechanical debridement (C) were approximately 21% (A), 98% (B) and 30% (C).[1]


Up to 69% removal of necrosis and devitalized tissue within 14 days*[1]


1 product instead of many: cleanses, debrides, desloughs wounds, absorbs exudates, binds bacteria[2–10]


Effective wound cleansing[2–5,7,9] and rapid debridement,[2,4,6,11–15]reduced pain during wear time[4–6,11,12,14–18], significant reduction of bacterial load[2,6,19] and biofilm[20]

*within 14 days compared to baseline

[1] Hodgson, H. et al. (2017). A multicentre, clinical evaluation of a hydro-responsive wound dressing: the Glasgow experience. Journal of Wound Care 26(11), pp. 643–650. [2] Atkin, L. and Ousey, K. (2016). Wound bed preparation: A novel approach using HydroTherapy. British Journal of Community Nursing 21(Supplt. 12), pp. S23–S28. [3] Ousey, K. et al. (2016). Hydro-Responsive Wound Dressings simplify T.I.M.E. wound management framework. British Journal of Community Nursing 21 (Supplt. 12), pp. S39-S49. [4] Spruce, P. et al. (2016). Introducing HydroClean® plus for wound-bed preparation: a case series. Wounds International 7(1), pp. 26–32. [5] Ousey, K. et al. (2016). HydroClean® plus: a new perspective to wound cleansing and debridement. Wounds UK 12(1), pp. 94–104. [6] Ousey, K. et al. (2016). HydroTherapy Made Easy. Wounds UK 12(4). [7] Humbert, P. et al. (2014). Protease-modulating polyacrylate-based hydrogel stimulates wound bed preparation in venous leg ulcers – a randomized controlled trial. Journal of the European Academy of Dermatology and Venereology 28(12), pp. 1742–1750. [8] Smola, H. (2016). Simplified treatment options require high-performance dressings – from molecular mechanisms to intelligent dressing choices. EWMA 2016. Bremen, 11–13 May, 2016. [9] Atkin, L. and Rippon, M. (2016). Autolysis: mechanisms of action in the removal of devitalised tissue. British Journal of Nursing 25(20), pp. S40–S47. [10] Kaspar, D. et al. (2015). Economic benefit of a polyacrylate-based hydrogel compared to an amorphous hydrogel in wound bed preparation of venous leg ulcers. Chronic Wound Care Management and Research 2, pp. 63–70. [11] Bullough, L. et al. (2016). A multi-centre 15 patient evaluation of a Hydro-Responsive Wound Dressing (HRWD) – HydroClean plus. HydroTherapy Symposium: A New Perspective on Wound Cleansing, Debridement and Healing. London, 3 March, 2016. [12] Scherer, R. et al. (2015). HydroTherapy®. Application study. Heidenheim: Paul Hartmann AG. [Data on file]. [13] Chadwick, P. and Haycocks, S. (2016). The use of Hydro-Responsive Wound Dressing for wound bed preparation in patients with diabetes. Wounds UK Annual Conference. Harrogate, 14–16 November, 2016. [14] Knowles, D. et al. (2016). HydroTherapy® wound healing of a post amputation site. Wounds UK Annual Conference. Harrogate, 14–16 November, 2016. [15] Zollinger, C. et al. (2014). HydroTherapy®. Application Study. Heidenheim: Paul Hartmann AG. [Data on file]. [16] Colegrave, M. et al. (2016). The effect of Ringer’s solution within a dressing to elicit pain relief. Journal of Wound Care 25(4), pp. 184–190. [17] O’Brien, D. and Clarke, Z. (2016). The patient experience with a Hydro-Responsive Wound Dressing (HRWD) – HydroClean® plus. HydroTherapy Symposium: A New Perspective on Wound Cleansing, Debridement and Healing. London, 3 March, 2016. [18] Jones, T. and McCracken, K. (2016). HydroClean® plus assists healing of leg ulcers for a patient with systemic lupus erythematosus. Wounds UK Annual Conference. Harrogate, 14–16 November, 2016. [19] Kaspar, D. et al. (2008). Efficacité clinique du pansement irrigo-absorbant HydroClean® active contenant du polyacrylate superabsorbant dans le traitement des plaies chroniques – étude observationnelle conduite sur 221 patients. Journal des Plaies et Cicatrisations 13(63), pp. 21–24. [20] Davies L. et al. (2017). An Assessment of Biofilm Disruption and Bacteriostatic Capabilities of an Autolytic Debridement Dressing. Wounds UK Annual Conference.Harrogate, 13–15 November, 2017.